Facilitated Tucking (FT) position as an innovative nursing approach and Gustatory Stimulation (GS) would mimic the feeling of being held within mother's hug. Purpose: To determine the effect of FT and GS on preterm neonates' physical growth and behavioral regulation.  Research Design: A quasi experimental design was used. Setting: This study was conducted at the Neonatal Intensive Care Unit (NICU) of Abo Hommos Hospital for Children, Damanhour City, Al-Behira Governorate, Egypt. Sampling: A consecutive sample of 60 preterm neonates who achieved the inclusion criteria were equally allocated into intervention and control groups. Instruments: Three instruments were used. Instrument one: Preterm Neonates' Characteristics and Medical Data Assessment Record. Instrument two: Preterm Neonates' Physical Growth Indices Record. Instrument three: Preterm Neonate's Behavior Assessment Scale. Results: Neonates in the intervention group gained greater weight at the second and last assessments than neonates in the control one, with the final assessment showed a statistically significant difference (p= 0.003). The percentage of neonates in the intervention group who exhibit normal behavior are greater than neonates in the control one at the second and last assessments. Conclusion: Facilitated tucking and GS for preterm neonates was effective in improving weight gain, autonomic visceral neurophysiological responses and state regulation and attention- interaction. Recommendation: Facilitated tucking and GS should be incorporated into the care of premature infants in NICUs.