Background: Kidney stones have been a widespread problem in recent years. Patients with kidney stone disease are
prone to several complications and percutaneous nephrolithotomy consider golden stander for the treatment of upper
urinary stones, but still has complications. Therefore, patient education is a crucial to decreasing postoperative
complications. Aim: to evaluate the effect of nursing protocol on knowledge and health outcomes of patient undergoing
percutaneous nephrolithotomy. Method: A randomized control trial study, sixty patients with kidney stones scheduled
for percutaneous nephrolithotomy were assigned into two equal groups of thirty each (study and control) at nephrology
and urology center at Mansoura University Hospitals. Tools: The study data was gathered using three tools. Tool I: A
Structured Interview Questionnaire. Tool II:Patients' Knowledge about Percutaneous Nephrolithotomy. Tool III:Clavien-
Dindo grading system for surgical complications classification. Results: Following introduction of the nursing protocol,
there was a significant improvement in knowledge within study group in compared to the control group, incidence of
complications mean score was statistical significant different between the two groups (0.003)), there was significant
relation between knowledge level and level of post-operative complications in the study group where P=0.037, There
was also a statistically significant relationship between the level of postoperative complications and the length of
hospital stay in the study group(P=0.035).Conclusion: After applying nursing protocol, patients undergoing
percutaneous nephrolithotomy improved significantly in their knowledge and post-operative health outcomes.
Recommendation: Nursing protocol should be integrated within the plan of care for renal stone patients undergoing
PCNL.