Background: Nurses are the professional group within the healthcare team. Nursing is an extremely stressful job by its
nature. Workplace stress is a prevalent and costly issue that can influence the quality of services delivered, induce
burnout, raise the likelihood of leaving work, absenteeism, and diminish the quality of nurses' work life. Aim: To use job
demand control support model to study nurses' job stress and its relations with their quality of work life at Magdy
Yacoub Heart Foundation. Design: Descriptive correlational design was carried out. Methods: Utilizing three tools, Job
Demands, Control and Support Scale, Nursing Stress Scale, and Work-Related Quality of Life Scale. Results: The
majority of nurses exhibit a high level of job demand and excellent level of job support, most of them had an excellent
level of job control, while most of them had a low level of job stress. About 53.9% of the studied nurses had a moderate
level of quality of work life. Conclusion: There are highly statistically significant negative relations between job control,
job support and job stress. Additionally, there are highly statistically significant negative relations between job stress and
quality of work life. Also, there is a highly statistically significant positive relation between job control, job support and
quality of work life while job demand had no statistically significant relation with job stress and quality of work life.
Recommendations: Create an environment that reduces excessive job demands, provides necessary control and fosters
the quality of work life among nurses through job support.