Introduction: Central line associated blood stream infection is responsible for increasing the mortality in
pediatric intensive care units, prolonged hospitalization and increasing healthcare expenses. Aim: The present study
aimed at studying knowledge and performance of healthcare professionals regarding infection control measures
associated with central venous catheter at pediatric intensive care units. Method: The study is a baseline assessment
survey for a larger study. Convenience sampling technique was used to recruit a total number of 10 physicians and 20
nurses, who were working at the intensive care units at pediatric hospital, Mansoura University. Results: The study
revealed that 40% of nurses showed poor knowledge level in relation to infection control measures associated with
central venous catheter and 35% of them showed incompetent performance level. Conclusion: Poor knowledge level and
incompetent performance among health care professionals regarding infection control measures of central venous
catheter at pediatric intensive care units. It is recommended to implement educational module on infection control
measures of central venous catheter at pediatric care units.