Background: Concerns about NICU mistreatment have arisen as a result of rising NICU admissions, longer
gestational ages, greater birth weights, and slowly decreasing disease acuity. To lower neonatal mortality in low- and
middle-income nations, hospitals must provide better treatment. Aim: To assess nurses' knowledge and practices about
immediate care bundle protocol for neonates. Method: A descriptive research design including fifty nurses and fifty
full-term newborns was carried out in the delivery room, surgery room, and neonatal care unit at Mansoura New
General Hospital.Using Tool I; A Structured Questionnaire sheet for nurses, and Tool II; Nurses Observational
checklists for nurses. Results: It was observed that the studied nurses had total mean score of Knowledge by
24.78±4.79 and total mean score of observational checklist was 47.48±10.83 about immediate care bundle protocol for
Neonates. Conclusion: It concluded that all graduate nurses had insufficient knowledge and unsatisfactory
performance immediate care bundle protocol for Neonates. There was also a strong positive correlation between
knowledge and achievement levels. Recommendation: There is a need to establish in-service training programs
related to well-designed immediate care packages for childcare and maternity care providers to develop caregiver
knowledge, attitudes and practices and adapt them to new concepts of care. there is. Nursing curricula should
incorporate current technology and update knowledge of recent advances as emergency care packages for pediatric
nurses.