Background: A stem cell is a master cell that has the ability to multiply and produce cell types, which continue to
differentiate and renew itself and can regenerate tissue with functional damage. This study aimed to assess the maternity
nurses' knowledge regarding cord blood collection. Study design: across sectional research design was utilized. Setting:
This study was conducted in labor and delivery unit of four governmental hospitals at Mansoura City Dakahlia
Governorate, Egypt. Study sample: A convenient sample included 53 nurses. Tool: Data were collected through a
structured interviewing questionnaire, included two parts: Part 1 sociodemographic characteristics of nurses and Part II
included nurses' knowledge about cord blood collection and stem cells. Results: : It was observed that 33.7% of nurse's
gained information from book, magazines and brochures, 41.5 % of the studied nurses had poor level of knowledge
regarding the umbilical cord, cord blood collection, technique of cord blood collection and stem cells 58.5% of the
studied nurses had negative attitude toward cord blood collection and stem cells Conclusion: Based on findings of the
present study, it concluded that most studied nurses had poor level of knowledge regarding the umbilical cord, blood
collection, technique of cord blood collection and stem cells. Recommendations. In-service training programs related to
cord blood collection and stem cells must established to improve nurses' knowledge. Simple booklets regarding cord
blood collection and stem cells should be available and easily access in labour units.