Background: COVID-19 presents challenges for the management of children with chronic kidney disease and acute kidney
injury requiring dialysis. Hemodialysis nurses play a pivotal role in the management of infection control at hemodialysis
units. Aim: Evaluate the effect of applying the care bundle on nurses' knowledge, attitude, and practice for children
symptomatic of COVID-19 under hemodialysis. Research design: A quasi-experimental (pre/post-test) design was utilized.
Setting: This study was applied at the Pediatric Unit of Hemodialysis, Benha University Hospital. Tools of data collection:
Tool (I): A Structured Interview Questionnaire: consists of part (1): characteristics of the studied nurses and part (2): Nurses'
Knowledge Assessment regarding hemodialysis, COVID-19, and infection control measures. Tool II: Nurses' attitude toward
children with Covid-19. Tool III: An Observational Checklist Sheet, adopted from the Center for Diseases Control and
Prevention and the International Society of Nephrology to assess the nurses' performance regarding the care of children due
to hemodialysis, and Tool (IV) for Child medical assessment. Results: The majority (88.6% & 71.4%) of studied nurses had
a satisfactory level of knowledge at post and follow-up phases as compared to pre-implementing the care bundle, as well as
most of them (92% & 80%) had a competent level of practice at post and follow-up phases. Regarding nurses' attitude, many
of them (85% & 70%) show a positive level of attitude at post and follow-up implementation of the care bundle as compared
to pre- implementation phase. Conclusion: Applying the bundle of care effectively improved the studied nurses' knowledge,
attitude, and practice regarding the care of children symptomatic with COVID-19 under hemodialysis at the post and followup
phases compared to pre-phase. Recommendation: Continuous in-service training regarding applying bundle of care on
nurses' knowledge, attitude, and practice for children symptomatic with COVID-19 under hemodialysis with periodic
follow-up is urgently needed.