Background: Chemotherapy-induced nausea and vomiting (CINV) is a common side-effect in different treatments
modalities for cancers. Reflexology is one of the non-pharmacological interventions that could be used to control CINV
among cancer patients. Aim: Evaluate effect of foot reflexology on chemotherapy-induced nausea and vomiting among
cancer patients. Methods: Quasi-experimental study with a purposive sample of totally 60 cancer patients from both
genders who were admitted to the Oncology Center of Mansoura University Hospital was enrolled in the study. Patients
were assigned to the intervention group (foot reflexology) and the control group (routine care). Data were collected using
a structured interview questionnaire and the Rhodes index for nausea and vomiting scale. Results: There was a
significant improvement in nausea and vomiting among the study group than control group according to the Rhodes
Index for nausea and vomiting scale as the p-value ≤ 0.05 after implementing foot reflexology sessions. Conclusion &
Recommendation: Foot reflexology has a good effect on chemotherapy-induced nausea and vomiting among cancer
patients and should be used as an adjuvant to daily care for cancer patients undergoing chemotherapy.