ABSTRACT: The traditional sand filter which used strictly in modern irrigation systems has many disadvantages that lead to reduce the removal efficiency through the filtration process. Designing and testing of a new proposed filter with three different filtration media is the main objective of this study, besides comparing its performance with the traditional sand filter. The study was conducted with two different irrigation water levels in quality which were Nile water and treated agricultural drainage water under two levels of water flow rate inside each filter which were 5 and 7 m3 h-1. The three different media of the new proposed filter were: first contains gravel layer with 13 cm thickness and mixed layer of gravel and sand with 13 cm thickness. The second media contains the same two layers besides a sand layer over lay it with 13 cm thickness, while the third media contains another layer of mixed gravel and resin with 11 cm thickness. The highest removal efficiency was 95.7% recorded with the new proposed filter under 5 m3 h-1 of Nile water flow rate, with the filtration media that contains four layers (gravel, mixed gravel and sand, sand only and gravel mixed with resin). The lowest removal efficiency (72.04%) was recorded with 7 m3 h-1 of treated agricultural drainage water flow rate with the traditional sand filter. The lowest pressure drop (3.75 kPa) was recorded with the new proposed filter after 900 h of operating times under 5 m3 h-1 of Nile water flow rate. The highest emitter clogging percent (50.13%) achieved with the traditional sand filter after 840 h of operating time under 7 m3 h-1 of Nile water flow rate. While the highest emitter clogging percent (51.63%) achieved after 1320 h with the new proposed filter with the four layers of filtration media under 5 m3 h-1 of Nile water flow rate. The highest total weight of lettuce was (686.70 g/plant) achieved with Nile water by the filtration media that contains four layers of the new proposed filter (gravel, mixed gravel and sand, sand only and gravel mixed with resin) under 5 m3 h-1 of water flow rate. The lowest total weight (512 g/ plant) was observed with treated agricultural drainage water by traditional sand filter treatment under 7 m3 h-1 of water flow rate.