Nature embraces enormous resources for biomimicry yet faces many challenges, including embodying and simulating environmental systems and processes into technical systems within the built environment. Also, imitation and mimicry strategies focus on separate parts rather than a complete system as an organism as a single unit in its environment. Therefore, the research aims to reduce the harmful effects of buildings and preserve biodiversity and energy through a systematic design technique for biomimicry to identify appropriate adaptation mechanisms from nature and inspire their functions, processes, and forms to integrate architecture and biology. Accordingly, the study addressed biomimicry through its entrances, classes, and levels depending on the desired result. The problems encountering biomimicry application and its adaptation mechanisms; were explained. Then, the information and characteristics required from nature were classified according to three biomimicry classes to implement environmental concepts and treatments. Likewise, the study compared the biomimicry strategies to choose the most suitable one for the design processes. Thus, it confirmed the correlation between green buildings and biomimicry. Finally, a systematic technique was derived and established to incorporate and collaborate between two approaches for simulating nature to identify the appropriate biological systems for attaining green building, improving design processes, and making decisions.