Poor ovarian reserve (POR) significantly limits the effectiveness of infertility treatments. Ovarian reserve assessment is vital for predicting the success of pregnancy following infertility treatments. The response to ovarian stimulation can partly reflect the success of IVF. Women who respond well to controlled ovarian hyperstimulation (COH) have a higher chance of pregnancy and live birth. Pretreatment with oral contraceptive pills (OCPs), progesterone, or ethinyl estradiol is used to improve follicular synchronization, prevent premature ovulation, and better schedule cycles. Ovarian stimulation protocols using GnRH analogs, both agonists and antagonists, come with drawbacks such as increased cost, daily injections, patient inconvenience, and potential adverse effects. Recent developments have introduced oral progesterone as a viable alternative to GnRH analogs for preventing LH surges.

AIM OF THE WORK:
The aim of the present study was to evaluate the efficacy of Progestin primed ovarian stimulation protocol versus GnRH antagonist protocol in low ovarian reserve patients undergoing ICSI cycles.