Features that are visible on brain tissue gross examination of people with MS included multiple highly delineated demyelinating plaques in the CNS white matter (WM), with an increased tendency of affection for the optic nerves and WM tracts of the peri-ventricular regions.

AIM OF THE WORK:
The aim of this study was to evaluate the diagnostic value of the 3D- FLAIR sequence in MS. Also, the correlation between lesion load on 3D- FLAIR and EDSS will be performed.
Our study will include 32 patients with MS.

PATIENTS AND METHODS:
MS lesions appear everywhere in the central nervous system wherever myelin is present, but lesions surrounding the ventricles and corpus callosum are particularly suspicious. Subcortical and infratentorial areas are also common areas of involvement.
This study includes 32 patients with MS. diagnosed clinically according to McDonald criteria modified in 2017
Inclusion criteria:
Definite diagnosis of MS according to 2017 Mcdonald criteria.
Exclusion Criteria:
Any other immunological, malignant, or vascular CNS diseases in the present and/or past medical history.