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354094

Evaluation of serum taurine level in patients with endometrial cancer

Article

Last updated: 26 Dec 2024

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Tags

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Abstract

Endometrial cancer is the most common type of uterine cancer
Risk factors of endometrial cancer: Obesity, Unopposed estrogen therapy, polycystic ovarian syndrome, Tamoxifen therapy, Hypertension, Diabetes mellitus, Pelvic radiation therapy and endometrial hyperplasia. Abnormal vaginal bleeding is a prevalent symptom in endometrial cancer, affecting roughly 90% of diagnosed patients. Physical examination commonly reveals an obese, hypertensive, postmenopausal woman, although approximately 35% of patients are not obese and show no signs of hyperestrogenism. Developing a screening tool of low cost, high feasibility, and high diagnostic accuracy for endometrial cancer is still a maturing area of research.
Laboratory Testing: Taurine (2-aminoethanesulfonic acid), a naturally occurring amino acid found throughout the body, plays a crucial role in ensuring the proper functioning of the central nervous system, retinal neurons, and cardiac and skeletal muscles. Recent research highlights additional benefits, including anti-inflammatory, antioxidant, and blood sugar control properties. Studies indicate it has the ability to inhibit cancer cell proliferation and induce apoptosis, which is programmed cell death Top of Formin certain cancers, possibly through regulation of proteins involved in cell death pathways. It's important to note that research on taurine's antitumor effects is in its early stages. The underlying mechanisms by which taurine exerts these effects are not fully understood. However, this initial research offers promising evidence and warrants further investigation into the potential clinical application of taurine in cancer treatment.

DOI

10.21608/alexpo.2024.287817.1834

Keywords

Evaluation, serum taurine, Endometrial cancer

Authors

First Name

Hossam

Last Name

Elsokary

MiddleName

Hassan

Affiliation

Obstetrics and gynecology faculty of medicine

Email

hossam.alsukari@alexmed.edu.eg

City

Alex

Orcid

-

First Name

Reham

Last Name

Abdelhalem

MiddleName

-

Affiliation

Department of Chemical and clinical Pathology, Faculty of Medicine, University of Alexandria

Email

reham.abdelhalem@alexmed.edu.eg

City

-

Orcid

-

First Name

Ahmed

Last Name

Essmat

MiddleName

Abdelazem

Affiliation

Department of Obstetrics and Gynecology, Faculty of Medicine, Alexandria University

Email

princeessmat@gmail.com

City

-

Orcid

-

First Name

Fatma

Last Name

Anter abdelrahman

MiddleName

Wahid

Affiliation

Obstetrics and gynecology faculty of medicine

Email

fatmawahid1990@gmail.com

City

-

Orcid

-

Volume

6

Article Issue

2

Related Issue

46999

Issue Date

2024-04-01

Receive Date

2024-05-07

Publish Date

2024-04-01

Page Start

14

Page End

15

Online ISSN

2682-2636

Link

https://alexpos.journals.ekb.eg/article_354094.html

Detail API

https://alexpos.journals.ekb.eg/service?article_code=354094

Order

1

Type

Preliminary preprint short reports of original research

Type Code

1,426

Publication Type

Journal

Publication Title

ALEXMED ePosters

Publication Link

https://alexpos.journals.ekb.eg/

MainTitle

Evaluation of serum taurine level in patients with endometrial cancer

Details

Type

Article

Created At

26 Dec 2024