Benign hematological disorders including Hemoglobinopathies and coagulation disorders are common in the pediatric population with different presentations.
Thalassemia is disorder resulting from globin chain synthesis impairment through the mutation or deletion of globin genes.
Sickle cell disease (SCD) is hematologic disorder caused by mutation that leads to the formation of abnormal hemoglobin S which cause sickling of erythrocytes.
Hemophilia is characterized by spontaneous and post-traumatic bleeding events into the joints, muscles, and soft tissues, which can lead to disability.
Chronic illness is significantly impacts millions of families and siblings each year. The impact of having an illness in the family extends across various aspects of life, including financial, physical, emotional, social, behavioral, and personal domains.
Health-related quality of life, or HRQOL, is likely to be a crucial factor when deciding how best to treat individual patients and how best to allocate health care resources for chronic disorders which there is no known cure and treatment may be extended. Research on child health services has acknowledged HRQOL as a significant health consequence.