Cannabis and tramadol have huge popularity in Egyptian community claiming their effects on sexual function and delayed ejaculation. The prevalence of tramadol use was 12.3% among university students, with higher prevalence in male (20.2%) than female students (2.4%). In a recent study on the lifetime prevalence of alcohol and substance use in Egypt, cannabis was the most misused drug, prevalence of cannabis abuse among general population is 7.25–14.5%.
Much research has found that tramadol can produce changes in gonadal hormone levels.Tramadol as an opioid may have negative effects on libido, erectile function (EF) and ejaculatory function. One research group has reported dose-related reduction in the plasma testosterone levels of male subjects after chronic intensive use of cannabis. However, other studies with human males have found testosterone levels to be within normal limits after marijuana usage.
In view of the contradictory reports of the effects of cannabis on sexual function and androgens. also encouraged by scarcity of Data about sexual effect of tramadol we decided to conduct this study.