Induction of labor (IOL) is one of the most frequent performed procedures in obstetrics. It is universally accepted that (IOL) is indicated when fetal and maternal outcomes are better than expectant management, which is waiting for spontaneous onset of labor. Before IOL is performed, informed consent should be made with good counselling about the risks and benefits for the method that will be used. Induction of labor is artificial stimulation of uterine contractions before onset of spontaneous labor for effective progressive effacement and dilatation of cervix and ultimately delivery of the feto-placental unit. There are many factors affecting the success of induction like pre-induction bishop score, parity, age of the mother, BMI, gestational age, fetal size and some biochemical markers such as: fibronectin, insulin like growth factor binding protein 1 and activin A. Various methods of induction are available; pharmacological and mechanical. Pharmacological methods use oxytocin, prostaglandin E1 (misoprostol) which can be administered through different routes (vaginal, buccal or sublingual) and dinoprostone which is also available in different forms (tablets, pessary, inserts and Gel).