Epilepsy is one of the most common diagnoses seen by pediatric neurologists. Magnetic resonance imaging (MRI) is the preferred imaging modality to detect structural abnormalities in patients with seizure because of its superior sensitivity for lesion detection. If the magnetic resonance (MR) result does not reveal structural abnormalities, identifying the epileptogenic zone is more challenging in these patients. Arterial spin labeling (ASL) is a magnetic resonance imaging (MRI) technique for assessing cerebral blood flow by magnetically labeling protons from the inflowing blood as an endogenous diffusible tracer. ASL is a safe and easily accessible modality, that can be used to assist with the localization of seizure focus.
Aim of the Work:
To assess the role of arterial spin labeling MRI perfusion in children with focal epilepsy particularly those with negative structural MRI studies.
Subjects and Methods:
Subjects:
This study was conducted on 20 children presenting with interactable focal epilepsy referred to radiology department for further MRI assessment.