A pre-operative clinical estimate of EC using specular microscopy can provide data regarding ECD and morphology, thus facilitating assessment of the functional reserve of the endothelium in individual patients. This analysis provides a measure of the general health of the corneal endothelium, which is important before any intraocular surgery and provide a baseline to predict post-operative outcomes of corneal state that influence patients' visual outcomes.
As an intraocular surgery, vitreoretinal surgery is associated with EC changes. During surgery, factors as intraocular irrigation solution and operation time may affect the corneal endothelium. Also, furthermore damage may be related to the used tamponade.
AIM OF THE WORK:
The aim of this study was to evaluate the corneal endothelial cell changes after pars plana vitrectomy operations and to compare the results using different types of tamponades (silicon oil and SF6 gas).
SUBJECTS AND METHODS:
This prospective study consisted of 50 eyes of patients undergoing pars plana vitrectomy surgery. The patients were assigned into two groups according to the retinal tamponade used:
Group I were silicon oil filled, and Group II were SF6 gas filled.
Central corneal endothelial cell density (ECD), central corneal thickness (CCT), mean cell density (MCD) and mean cell area (MCA), and coefficient of variation (polymegathism) and cell shape (polymorphism) were measured using a non contact specular microscope, preoperative, one month and three month postoperatively.