INTRODUCTION
Cholecystolithiasis, refers to the presence of stones in the gallbladder. Several non-invasive methods were developed for removal or destruction of the stones without removing the gallbladder, however cholecystectomy remains the treatment of choice.
Laparoscopic cholecystectomy is the gold standard for the treatment of symptomatic gallbladder stones on the facts that it reduces anesthesia and operative times, reduces blood loss, reduces hospital stay, reduces tissue trauma and adhesion formation, improves the cosmetic aspect, and makes the patient to take less medication and resume earlier their daily activities.
Several techniques have been developed to control and divide the cystic duct and cystic artery. The use of metallic clips to control the cystic duct and artery has substantially facilitated laparoscopic cholecystectomy and is most commonly used method nowadays. Several studies have reported the use of high-power ultrasonic shear to control cystic duct and artery in what became known as “clipless cholecystectomy".

AIM OF THE WORDK
The aim of this prospective randomized study is to assess the safety and feasibility of using a harmonic scalpel for control of the cystic duct and artery compared to conventional clips during laparoscopic cholecystectomy.