In the Middle East, PCG incidence is one of the highest in the world, markedly increasing in populations with high consanguinity especially cousin-cousin inbreeding. Despite this, 90% percent of PCG cases occur sporadically without any family history. Only 10% show AR inheritance with variable penetrance.
Clinical presentation of PCG varies according to severity of the condition. Tearing, eye rubbing, photophobia, irritability and covering eyes in sunlight are common symptoms observed by parents or caregivers. Discrepancy between both eyes, corneal clouding and globe enlargement may be also attract the parent's attention.
Management is mainly surgical as medical treatment is rarely effective and associated with high risk of adverse effects. Surgical treatment options include angle surgery, filtering surgery and cyclodestructive procedures. Management should not aim only to lower the IOP, but also to manage any secondary complications including amblyopia, refractive changes, corneal clouding, and buphthalmos.
Aim:
The aim of this study was to assess the long-term outcome of operated primary congenital glaucoma cases after a follow-up period of at least 8 years.