This study was to evaluate some sugar beet varieties to powdery mildew infection caused by Erysiphe betae under greenhouse conditions at Gemmeiza Agricultural Research Station, A.R.C. during 2021/2022 growing seasons. Fourteen sugar beet varieties (Belatos, Heba, Gazelle, Aminavhe, Oscar poly, Ribera, Puma, Toro, Lilly, Carnute, Ninagri, Dreeman, Kara and Hercules). The disease severity (DS%) was recorded at four times 14 day post artificial inoculation with Erysiphe beta. In addition, the areas under disease progress curve (AUDPC). The disease severity (DS%) at 105 days, sugar beet varieties can be categorized into three groups (resistant, moderate, and susceptible). The resistant varieties were Dreeman, Puma, Ribera, Lilly, Toro and Oscar poly. The moderately resistance varieties included Carnute, Heba, Gazelle, Ninagri, Kara, Belatos and Aminavhe. On the other hand, the maximum DS was recorded in Hercules variety. This means that Hercules variety was the most susceptible one to powdery mildew disease. According to the area under disease progress (curve), sugar beet varieties can be categorized into four groups as follows: resistant varieties (Dreeman, Puma and Ribera), moderately resistant (Lilly, Toro and Oscar poly), moderately susceptible (Carente, Heba, Gazelle, Ninagri, Belatos and Aminavhe), and susceptible (Hercules). As a result, the highly susceptible variety showed high levels of Final disease severity (FDS%) such as Heracles while the lowest of FDS were Derrman, puma, Ribera, Lilly, Toro and Oscar poly. The highest root yield (10.83Kg/plot) was achieved by Carnute varieties, while the lowest yield was observed in Hercules variety. Among sugar beet varieties, Heba attained the maximum TSS (19.66 %), while Hercules variety had the lowest TSS in the same time Oscar poly was the highest purity (90.46) while Hercules was the lowest in this respect (80.91). The highest sucrose concentration was observed in Heba variety, while Hercules variety possessed the lowest. Data Showed that Chl.a all sugar beet varieties non significantly in thesis respect. Howe ever varieties Dreeman, Carmute and Ribera gave the heighest concentration. In the same manner, Chl. b concentration was significantly increased due to sugar beet varieties. The heighest concentration was recorded varieties Puma, Dreeman, Oscar poly and Ribera While the lowest recorded concentration Chl. b varieties Hercules, Kara and Ninagri. Chl. a +b all varieties non significantly. While the lowest concentration of Chl. a +b were recorded varieties Hercules. Carotene concentration was significantly increased due to sugar beet varieties. The heighest concentration were recorded in varieties Dreeman, Ribera, Carnute and Oscar poly.