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323713

EFFECT OF ETHANOLIC DATURA LEAVES EXTRACT ON STERILANT OF WHITE NORWAY RAT, RATTUS NORVEGICUS

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Last updated: 04 Jan 2025

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Abstract

Abstract: The effect of ethanolic Datura leave extract, Datura stramonium, was studied on the fertility of albino rat males and teratogenic effect on the pregnant female of white Norway rat, Rattus norvegicus. Results showed that LD50 values were 116.70 mg/kg body weight. The results cleared that the treatment of male albino rats with sub-lethal doses (1/10 and 1/4 LD50) of tested extract decreased the pregnancy rate and also reduced the weight of males testes. Also, the obtained data from the treated pregnant female rats with the same sub-lethal doses have potential harmful effects on the fetuses in addition to fetal retardation of  embryonic formation and development inside the uterus of the pregnant females especially in the first week followed by the second and third weeks. The resorption effects were observed inside the uterus of the pregnant female when compared with those of untreated pregnant females. Also, the tested plant extract reduced the number of newly born individuals and the weight of fetuses.

DOI

10.21608/mjapam.2015.323713

Keywords

Datura extract, sterilant- Rattus norvegicus

Authors

First Name

A. A.

Last Name

Mourad

MiddleName

-

Affiliation

Plant protection Research Institute, Agric. Res. Center, Egypt

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Orcid

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Volume

40

Article Issue

2

Related Issue

44003

Issue Date

2015-04-01

Receive Date

2015-01-06

Publish Date

2015-04-01

Page Start

483

Page End

489

Print ISSN

2357-0776

Online ISSN

2735-3494

Link

https://mjpam.journals.ekb.eg/article_323713.html

Detail API

https://mjpam.journals.ekb.eg/service?article_code=323713

Order

2

Type

Original Article

Type Code

1,417

Publication Type

Journal

Publication Title

Menoufia Journal of Plant Protection

Publication Link

https://mjpam.journals.ekb.eg/

MainTitle

EFFECT OF ETHANOLIC DATURA LEAVES EXTRACT ON STERILANT OF WHITE NORWAY RAT, RATTUS NORVEGICUS

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Article

Created At

26 Dec 2024