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323994

BENEFITING OF SOME PLANT MATERIALS IN IMPROVING LIVER FUNCTIONS FOR HEPATICALLY TOXICATED RATS WITH CCL4

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Last updated: 26 Dec 2024

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Abstract

ABSTRACT:The present study investigated the effects of carrot (Daucus carota, L.), prickly pear (Opuntia ficus-indica, L.) and chicory (Cichorium intybus, L.) on CCl4 induced hepatotoxicity in rats. Forty five male albino rats were divided into 9 groups (five rats in each group). Two groups were controls, one fed on basal diet only (negative control) and the other fed on basal diet after injection with CCl4 (positive control). The other groups were injected by CCl4 then received basal diet containing carrot, chicory and prickly pear at the levels 10, 15% and 15% mixture of the tested plants. Liver damage was assessed by estimation for the plasma concentration of enzymes activities of aspartate amino transferase (AST), alanine amino transferase (ALT), lipid fraction (total cholesterol and triglyceride), cholesterol fraction (HDL-c, LDL-c, VLDL-c), Uric acid, Urea nitrogen and glucose. Results showed an improvement in case of prickly pear followed by carrot and chicory for the above parameters.  The best level was 15% of these plants followed by 10% of tested plants. So, this study concluded that CCl4 induced liver damage in rats can be ameliorated by administration of 15% prickly pear, carrot and chicory.

DOI

10.21608/mjfds.2015.323994

Keywords

Carrot, Prickly pear, Chicory, Liver damage, Cholesterol fraction, glucose

Authors

First Name

M. M.

Last Name

El-Sayed

MiddleName

-

Affiliation

Nutrition and Food Science, Faculty of Home Economics, Minufiya University

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Orcid

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First Name

, Nehad R

Last Name

. El-Tahan

MiddleName

-

Affiliation

Nutrition and Food Science, Faculty of Home Economics, Minufiya University

Email

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City

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Orcid

-

First Name

Asmaa M. A.

Last Name

Lasheen

MiddleName

-

Affiliation

Nutrition and Food Science, Faculty of Home Economics, Minufiya University

Email

-

City

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Orcid

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Volume

40

Article Issue

3

Related Issue

44163

Issue Date

2015-06-01

Receive Date

2015-03-15

Publish Date

2015-06-01

Page Start

667

Page End

678

Print ISSN

2357-0792

Online ISSN

2735-3486

Article File

MJFDS_Volume 40_Issue 3_Pages 667-678.pdf

PDF . 467.4kB

Link

https://mjfds.journals.ekb.eg/article_323994.html

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https://mjfds.journals.ekb.eg/service?article_code=323994

Order

2

Type

original papers

Type Code

1,406

Publication Type

Journal

Publication Title

Menoufia Journal of Food and Dairy Sciences

Publication Link

https://mjfds.journals.ekb.eg/

MainTitle

BENEFITING OF SOME PLANT MATERIALS IN IMPROVING LIVER FUNCTIONS FOR HEPATICALLY TOXICATED RATS WITH CCL4

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Article

Created At

26 Dec 2024