The researcher's goal for completing this study was to figure out the main critical success factors (CSFs) for applying Flexible Work Arrangements (FWAs) in Egypt on Academic Staff members at some Egyptian Universities (Public & Private). The researcher grouped the CSFs into two main groups which are: (1) Organizational Factors (Manager Support, Co-worker Cooperation, Organizational Culture and Technology Availability) and (2) Employee Factors (Employee Needs and Employee Commitment). The research also covers their relationship with FWAs implementation, including three main types (Flex-time, Telework and Part-time work) being used extensively in the higher education sector following COVID 19 Pandemic.    This is a descriptive quantitative study, and data was collected through a questionnaire. Its validity and reliability were verified, distributed to (n=343) academic staff members, and the study of the hypotheses were tested using simple linear regression and Pearson Correlation via SPSS software version 20. The hypothesis testing sought to establish a relationship between the aforementioned factors and the implementation of FWAs.   The researcher discovered that there is a significant positive relationship between Organizational Factors and FWAs implementation, but no significant relationship between Employee Factors and FWAs implementation, indicating that manager support is the most significant factor in implementing FWAs.   Before and during the implementation of FWAs, universities must ensure that managers support the system by providing training, raising awareness of its importance and highlighting its benefits to employees and the entire organization.