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353787

Effect of Intermittent Fasting on Weight Loss and Maintenance of the Lost Weight in Overweight and Obese Individuals: A Systematic Review and Meta-analysis

Article

Last updated: 04 Jan 2025

Subjects

-

Tags

COMMUNITY, ENVIRONMENTAL & OCCUPATIONAL MEDICINE

Abstract

Background: Long-term continuous caloric restriction (CCR) has demonstrated efficacy in reducing body weight in obese individuals. Adhering to daily CCR proves challenging in practical situations. Recent research suggests that intermittent fasting (IF) could enhance adherence to dietary restrictions. Objective: The aim of this meta-analysis was to investigate the impact of IF interventions in comparison to the conventional CCR on weight loss and the sustenance of lost weight among overweight or obese individuals. Methods: Comprehensive search was conducted in the PubMed, Web of Science, Scopus and Cochrane Central Register of Controlled Trials databases. After removing duplicates, we excluded studies that did not have a randomized controlled design, studies involving animals or individuals under eighteen years, and studies published in languages other than English. The final included studies were 12 randomized controlled clinical trials (RCTs). Results: Among the 12 studies, only one demonstrated a noteworthy reduction in body weight (BW) with the IF protocol compared to CCR. No significant differences were observed in terms of body mass index (BMI) reduction or waist circumference (WC) reduction across the studies. IF exhibited significantly better results of weight loss maintenance (WLM) in only one study. Conclusion: IF and CCR demonstrate similar reductions in BW, BMI, and WC. IF emerges as an appealing alternative to traditional CCR for weight control. WLM remains underexplored and necessitates dedicated RCTs. Larger clinical trials are essential to determine whether certain individuals respond more favorably to IF compared to CCR

DOI

10.21608/asmj.2024.271314.1226

Keywords

Intermittent fasting, Meta-Analysis, Continuous Caloric Restriction, weight loss maintenance, Ain Shams university

Authors

First Name

Ayat

Last Name

Manzour

MiddleName

Farouk

Affiliation

Department of Community, Environmental and Occupational Medicine, Faculty of Medicine, Ain Shams University, Cairo, Egypt.

Email

ayatfaroukm@yahoo.com

City

-

Orcid

0000-0001-6081-9016

First Name

Dina

Last Name

Boulos

MiddleName

Nabih Kamel

Affiliation

Department of Community, Environmental and Occupational Medicine, Faculty of Medicine, Ain Shams University, Cairo, Egypt.

Email

dnkamel@med.asu.edu.eg

City

-

Orcid

-

First Name

Waleed

Last Name

Salah- El Din

MiddleName

-

Affiliation

Department of Community, Environmental and Occupational Medicine, Faculty of Medicine, Ain Shams University, Cairo, Egypt.

Email

waleedsalah3333@hotmail.com

City

-

Orcid

-

First Name

Mohamed

Last Name

Allam

MiddleName

Farouk

Affiliation

Department of Community, Environmental and Occupational Medicine, Faculty of Medicine, Ain Shams University, Cairo, Egypt.

Email

farouk.allam@med.asu.edu.eg

City

-

Orcid

0000-0001-5954-8909

Volume

75

Article Issue

1

Related Issue

47552

Issue Date

2024-03-01

Receive Date

2024-02-22

Publish Date

2024-03-01

Page Start

131

Page End

140

Print ISSN

0002-2144

Online ISSN

2735-3540

Link

https://asmj.journals.ekb.eg/article_353787.html

Detail API

https://asmj.journals.ekb.eg/service?article_code=353787

Order

353,787

Type

Original Article

Type Code

1,311

Publication Type

Journal

Publication Title

Ain Shams Medical Journal

Publication Link

https://asmj.journals.ekb.eg/

MainTitle

Effect of Intermittent Fasting on Weight Loss and Maintenance of the Lost Weight in Overweight and Obese Individuals: A Systematic Review and Meta-analysis

Details

Type

Article

Created At

26 Dec 2024