Background: Colposcopy-directed biopsy is considered the definitive test for diagnosing cervical cancer (CC) as it reveals the architectural arrangements of abnormal cells. The majority of females developing cervical cancer have reported not being screened for 5 years at least.
Aim: To investigate the role of Colposcopy in early detection and diagnosis of pre-cancerous lesions with or without viral infection compared with Pap smear.
Patients and methods: The current study was designed as cross-sectional study that included 90 females who attended the Early Detection of Cancer Unit of Al- Zahra'a University Hospital between the start of March 2020 and the end of December 2021. Colposcopy and Pap smears were performed upon the detection of abnormally stained areas after the cervix has been stained with acetic acid (VIA) and lugol's iodine (VILI), multiple cervical biopsies were obtained from the suspicious areas.
Results: Our study revealed that Abnormal Colposcopy is 99.6% sensitive and 33.3% specific with positive predictive values 42.8% and negative predictive values of 1.2. Conclusions: Colposcopy has high accuracy in detecting cervical pre-malignant lesions than Pap smear. The use of colposcopy directed biopsy is recommended in screening for malignant and premalignant lesions of the cervix.