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339792

Evaluation of role of combined PET/CT Scanning in Identification of Osseous and Marrow Metastatic Deposits

Article

Last updated: 26 Dec 2024

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Tags

DIAGNOSTIC & INTERVENTIONAL RADIOLOGY

Abstract

Background: To improve a patient's long-term survival and reduce potential hematological, neurological, and orthopedic challenges, early cancer identification is critical. Osseous and marrow deposits are frequently seen as significant cancer consequences that can cause excruciating pain and have a bad prognosis.
Objectives: The study's objective was to show how combined 18F-FDG PET/CT is superior to standalone CT in detecting osseous and marrow deposits in cancer patients.
Patients and Methods: There were 75 participants in the trial, and 18F-PET/CT scans were carried out. Retrograde lesion-based analysis was carried out. The negative predictive value (NPV), positive predictive value (PPV), sensitivity, and specificity of each of these modalities were assessed as part of the statistical study. Whenever feasible, a biopsy of the underlying neoplastic lesion, pattern of dissemination, and follow-up were used to confirm a final diagnosis of metastasis.
Results: The detection of osseous and bone marrow metastatic deposits which are not visible on traditional CT studies is made possible by combined PET-CT examination, an extraordinarily sensitive imaging technique.
Conclusion: The identification of osseous and bone marrow metastases was reported to be substantially more sensitive and specific with combined 18-F FDG PET/CT than with standalone CT. In order to start a treatment regimen and improve the overall prognosis and result of the illness process, it adds a major value that can detect lesions.

DOI

10.21608/asmj.2023.233992.1164

Keywords

PET/CT, osseous, marrow metastatic lesions, Cancer

Authors

First Name

Sherine

Last Name

Sharara

MiddleName

M.

Affiliation

Assistant Professor of Diagnostic and Interventional Radiology - Faculty of Medicine - Ain Shams University, Cairo, Egypt.

Email

sherinsharara@yahoo.com

City

-

Orcid

-

First Name

Mostafa

Last Name

Abdelfadil

MiddleName

Abdelwahab Hussein

Affiliation

Diagnostic and Interventional Radiology Department - Faculty of Medicine - Ain Shams University, Cairo, Egypt.

Email

mostafafadil12@gmail.com

City

-

Orcid

-

First Name

Heba

Last Name

Elnaggar

MiddleName

-

Affiliation

Lecturer of Diagnostic and Interventional Radiology - Faculty of Medicine - Ain Shams University, Cairo, Egypt.

Email

hebaelnaggar68@gmail.com

City

-

Orcid

Hebaelnaggar2023

Volume

74

Article Issue

4

Related Issue

45902

Issue Date

2023-12-01

Receive Date

2023-09-03

Publish Date

2023-12-01

Page Start

987

Page End

998

Print ISSN

0002-2144

Online ISSN

2735-3540

Link

https://asmj.journals.ekb.eg/article_339792.html

Detail API

https://asmj.journals.ekb.eg/service?article_code=339792

Order

339,792

Type

Original Article

Type Code

1,311

Publication Type

Journal

Publication Title

Ain Shams Medical Journal

Publication Link

https://asmj.journals.ekb.eg/

MainTitle

Evaluation of role of combined PET/CT Scanning in Identification of Osseous and Marrow Metastatic Deposits

Details

Type

Article

Created At

26 Dec 2024