Background: Adnexal masses are common incidental finding during imaging, which cause diagnostic dilemma. Appropriate preoperative evaluation to discriminate between benign and malignant adnexal masses helps to decide the best management and improves survival rate. The most accurate diagnostic method is the contrast MRI to differentiate benign from malignant adnexal masses. Contrast MRI is contraindicated in patients with chronic kidney diseases as well as it may cause allergic reactions. In addition, contrast studies need more time and are expensive. So, Non-contrast MRI may be a diagnostic alternative method when the administration of intravenous contrast medium is not possible. Aim of the Work: Detection of the sensitivity and specificity of abbreviated non-contrast MRI compared with contrast MRI study in evaluation of adnexal masses by using non-contrast and O-RADS scoring systems with detection of inter-reader agreement. Patient and Methods: This study included 30 patients had adnexal masses with age ranging from 18 to 78 years, referred to MRI unit in Ain Shams University Hospitals from February 2022 to January 2023. Comparison between Non-Contrast MRI and ORADs scoring system was done to interpret sensitivity and specificity of non-contrast MRI study. Comparison between readers was done to interpret inter-reader agreement. Results: Non-Contrast MRI study compared with Contrast MRI study showed high specificity (92.3%), high sensitivity (100%) and high accuracy (95%). There was no statistically significant difference found between contrast & non-contrast MRI with high inter-reader agreement. Conclusion: Non-contrast MRI has high accuracy and high inter-reader agreement for characterization of adnexal masses. So, Non-Contrast MRI can be a safe alternative method when contrast use is contraindicated.