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285646

PROPHYLACTIC POTENCY OF METHANOLIC EXTRACT OF Momordica balsamina L. AGAINST AVIAN PARAMYXOVIRUS-1 INFECTION IN BROILER CHICKENS

Article

Last updated: 04 Jan 2025

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Subjects

-

Tags

Husbandry and veterinary science.

Abstract

The potency of Momordica balsamina extract against avian paramyxovirus-1 (Newcastle Disease Virus) (Kudu 113) was investigated in this study. Thirty, 5-week-old broiler birds were used for the experiment and were grouped in a completely randomised design with each group consisting of 5 birds. Group, I was a positive control, and group II was the negative control. The extract was administered prophylactically at doses of 200, 250, 300 and 350 mg/kg bw to groups III to VI respectively. Thereafter, all the groups were challenged with the strain of ND (Kudu 113) virus on seventh week to induce infection. The birds were monitored for 21 days for the symptoms of Newcastle Disease. No hemorrhagic lesion on the liver of all the groups administered with the extract was observed except group III which was administered 200 mg/kg BW of the extract. The mortality rate was 20% in group VI and 40% in group V. The clinical sign score was between 1 and 2 in groups III to VI and there was a significant difference (p < 0.05) in the level of cholesterol and Alkaline Phosphatase (ALP) in the groups administered with the extract and the positive control (Group I) though there were no significant differences (p>0.05) in the level of Aspartate transaminase (AST). Low levels of serum ALP and Alanine transferase (ALT) were also observed in the groups administered with the various doses of the extract compared to the positive control. The study demonstrated the potency of Momordica balsamina extract against the avian paramyxovirus -1 in the experiment.

DOI

10.21608/ejap.2023.163641.1049

Keywords

Avian paramyxovirus-1, Broiler Chicken, methanolic extract, Momordica balsamina, vaccine

Authors

First Name

Titus

Last Name

Ampitan

MiddleName

-

Affiliation

Federal College of Wildlife Management, Forestry Research Institute of Nigeria, P.M.B. 268, New Bussa, Niger State, Nigeria

Email

agbeoko@yahoo.com

City

NEW BUSSA

Orcid

0000-0003-2915-759X

First Name

Muhammad

Last Name

Garba

MiddleName

Haruna

Affiliation

Department of Biochemistry, Federal University Dutse, P.M.B. 7156, Jigawa State, Nigeria

Email

mharunagarba@gmail.com

City

Jigawa

Orcid

0000-0001-5590-4478

First Name

Dende

Last Name

Adekambi

MiddleName

Ibrahim

Affiliation

Ecole de Foresterie Tropicale, Universite Nationale d&rsquo;Agriculture, Porto &ndash; Novo, Benin Republic

Email

adekambidende@yahoo.com

City

Porto-Novo

Orcid

-

First Name

Abosede

Last Name

Ampitan

MiddleName

-

Affiliation

Department of Forestry Technology, Federal College of Forestry, Forestry Research Institute of Nigeria, P.M. B. 5087, Ibadan, Nigeria

Email

aaampitan@gmail.com

City

Ibadan

Orcid

-

First Name

Kehinde

Last Name

Adelakun

MiddleName

-

Affiliation

Federal College of Wildlife Management of Forestry Research Institute of Nigeria P.M.B. 268,

Email

adelakunkehinde@gmail.com

City

New Bussa

Orcid

0000-0001-8363-1710

Volume

60

Article Issue

1

Related Issue

39601

Issue Date

2023-02-01

Receive Date

2022-09-18

Publish Date

2023-02-01

Page Start

25

Page End

32

Print ISSN

0302-4520

Online ISSN

2735-3028

Article File

EJAP_Volume 60_Issue 1_Pages 25-32.pdf

PDF . 420.8kB

Link

https://ejap.journals.ekb.eg/article_285646.html

Detail API

https://ejap.journals.ekb.eg/service?article_code=285646

Order

4

Type

Original Article

Type Code

1,298

Publication Type

Journal

Publication Title

Egyptian Journal of Animal Production

Publication Link

https://ejap.journals.ekb.eg/

MainTitle

PROPHYLACTIC POTENCY OF METHANOLIC EXTRACT OF Momordica balsamina L. AGAINST AVIAN PARAMYXOVIRUS-1 INFECTION IN BROILER CHICKENS

Details

Type

Article

Created At

25 Dec 2024