Green Supply Chain (GSC) is increasingly implemented in healthcare industry. This paper attempts to develop a theoretical framework for analyzing the relationship between management information systems (MIS) and green supply chain management (GSCM): green service supply chain management (GSSCM) for performance enhancement of both Governmental and Private hospitals in Gharbia Governorate/Egypt. A Proposed Research framework based on the literature review of many previous studies related to research variables is explored for analyzing the relationship among MIS, GSSCM and OP for Egyptian healthcare industry. Based on the proposed conceptual framework and reviewed literature, research hypotheses are being developed.  Two statistical techniques are adopted for data analyzing; (SEM) to perform the required statistical analysis of data from the survey and Alpha test for ensuring construct validity and reliability. The statistical Package for the Social Sciences (SPSS) version21 is used to analyze the preliminary data and provide descriptive analyses about sample such as means, standard deviations, and frequencies. SEM using AMOS 6.0 is used to test the measurement model. Research population is comprised in Governmental and Private Hospitals in Gharbia Governorate/ Egypt. Sampling methods will be using a structured questionnaire to be distributed to respondents. Finally the researcher discusses and suggests future research work.