Histopathology studies the microscopic alteration of cells in tissue organs of living beings. Because of their economic significance and ability to be used as a model to predict the sensitivity of wild bird species to chemical contamination, chickens were chosen for this study. The present study was carried into control and treated chick embryos with two concentrations of hydrocarbon wastes for tissue organs (liver and brain). The results showed that PAHs have pathological effects represented by hydropic degenerative changes, necrotic tissue area, and congestion of blood vessels in the liver and brain. The pathological changes have been severed in group B (4ppm/egg of PAHs) compared with group A (2ppm/egg of PAHs). These results suggest that chick embryo liver and brain are sensitive to hydrocarbon's adverse effects.