391689

The Evaluation of COVID Medications’ Impact on the Liver Enzymes: A Study on Patients in Al-Ramadi Hospital, Iraq

Article

Last updated: 04 Jan 2025

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Tags

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Abstract

This research aims to evaluate the liver enzymes in patients who have recovered from COVID-19 compared to healthy controls. The sample included 69 COVID-19 survivors with liver failure, aged 26 to 66 years (mean age 47.61 ± 11.69). 67 healthy adults aged 19 to 62 years (mean age 36.33) were compared. Pearson correlation (with some differences from Spearman's method) was used to determine the relationship between liver failure and the drugs used during treatment (ceftriaxone, azithromycin, levofloxacin, and remdesivir). The results showed significant differences in ALT, AST, and ALP levels (p<0.001), between the two groups. In recovered patients, ALT is associated with ceftriaxone (R = 0.443, p<0.001) and remdesivir (R = 0.441, p<0.001). AST levels are similarly associated with ceftriaxone (R = 0.529, p<0.001), remdesivir (R = 0.455, p<0.001), and azithromycin (R = 0.366, p<0.001).

DOI

10.21608/jbaar.2024.391689

Keywords

liver enzymes, COVID-19, ceftriaxone, ALT, AST

Authors

First Name

Mohammed

Last Name

Mohammed

MiddleName

Hashim

Affiliation

Department of Medical Laboratory Techniques, Al-Maarif University College, Iraq

Email

m_famy@hotmail.com

City

-

Orcid

-

First Name

Bilal

Last Name

Aldahham

MiddleName

Jasir Mohammed

Affiliation

Department of Applied Chemistry, College of Applied Sciences, University of Anbar, Iraq.

Email

bilalaldahham@uoanbar.edu.iq

City

-

Orcid

-

First Name

Hussein

Last Name

Abed

MiddleName

Salim

Affiliation

Department of Medical Laboratory Techniques, Al-Maarif University College, Iraq

Email

-

City

-

Orcid

-

Volume

10

Article Issue

5

Related Issue

51933

Issue Date

2024-12-01

Receive Date

2023-12-25

Publish Date

2024-12-01

Page Start

57

Page End

62

Print ISSN

2356-9174

Online ISSN

2356-9182

Link

https://jbaar.journals.ekb.eg/article_391689.html

Detail API

https://jbaar.journals.ekb.eg/service?article_code=391689

Order

391,689

Type

Original Article

Type Code

1,272

Publication Type

Journal

Publication Title

Journal of Bioscience and Applied Research

Publication Link

https://jbaar.journals.ekb.eg/

MainTitle

The Evaluation of COVID Medications’ Impact on the Liver Enzymes: A Study on Patients in Al-Ramadi Hospital, Iraq

Details

Type

Article

Created At

25 Dec 2024