Aim: The use of chitosan gel may be considered as a new local chemotherapeutic material for the treatment of chronic periodontitis patients. This study aimed to evaluate the clinical effects of 1 % chitosan gel in treating intrabony defects in periodontitis. Materials and Methods: 30 patients were allocated into two distinct cohorts. Group I comprised 15 participants who underwent scaling, root planning, and intrapocket administration of chitosan gel. The Control Group encompassed 15 individuals who received scaling and root planning. Subsequently, all subjects underwent the initial phase of therapy and were educated on a regimen for controlling plaque. They were then assessed clinically at baseline, as well as at 3- and 6-months post-treatment. Results: Clinical parameters, including probing depth and clinical attachment level, were documented at baseline, 3 months, and 6 months. Significant statistical variances were observed within each group across the different time points in comparison to the baseline measurements. Particularly, probing depth exhibited a notable difference in Group I compared to Group II at the 3-month mark. Regarding clinical attachment level, Group I displayed a significant contrast with Group II at the 3-month interval, and a comparable distinction was noted between the two groups at the 6-month evaluation.
Conclusions: Intrapocket application of chitosan gel 1 % appeared to be effective adjunctive in the treatment of stage II to III chronic periodontitis.
Clinical Relevance: Topical application of chitosan gel provides a pivotal role in the treatment of periodontitis.