The term "multi-hazard risk analysis" refers to a comprehensive concept that includes the analysis of the risks in a given time and place, their size, the description of how they interact and the interpretation of the cumulative effects on a target group. It builds on single-hazard analysis and produces results that go beyond the simple sum of its elements. Extreme hazards are defined as those whose statistical significance is exceptionally high or which exceed a predetermined threshold. Multi-hazard risk analysis is a general term that refers to the analysis of the dangers in a given time and place, their magnitude, the description of how they interact and the interpretation of the results of this compounding on a target group. The basin of Wadi El-Ambagi is located east of the city of El-Quseir, on the Red Sea coast, between the Hurghada and Marsa Alam Cities. The basin extends from 25° 40´ to 26° 15´ N and from 33° 45´ to 34° 15´ E, and it covers about 1930 km2. The objective of this paper is to build a model of the multiple hazards risk resulting from the flash floods on the Wadi El-Ambagi basin, and analyze their effects on the road connecting the cities of El-Quseir and Qift, as well as the archaeological observation points built by the Romans to secure the gold mines road in Wadi El-Hamamat. The multi-hazard risk analysis can be categorized as qualitative, quantitative, and semi-quantitative, in addition to field geomorphic surveying, RS interpretation and GIS mapping.