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331249

Comparative Study between Effect of Dexamethasone and Betamethasone used for Fetal Lung Maturity on Daily Fetal Movement Count and Doppler Flow Velocity Waveforms

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Last updated: 25 Dec 2024

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Abstract

Preterm birth is the costliest complication of pregnancy and the leading cause of neonatal morbidity and mortality. There are multiple strategies to minimize the risk and the impact of prematurity, such as administration of antenatal corticosteroids (ACS), in association with tocolysis, neuroprotection with magnesium sulphate, and neonatal life-saving therapies. The main objective of this paper is to compare between effect of administration of dexamethasone and betamethasone, used for lung maturity on daily fetal movement count and fetal doppler flow velocity waveforms of umbilical artery and middle cerebral artery. Patients and methods: This was a Double blinded prospective comparative trial, was carried out at the Department of Obstetrics & Gynecology at Al- Obour Hospital for health insurance in Kafr Elsheikh & at Bab AL-Sharia University Hospital, on 100 pregnant women with indication for corticosteroid according to American college of obstetrics and gynecologists (ACOG) pregnant women between 24 weeks and 33 weeks of gestation associated with fetal lung immaturity) divided into 2 groups from 1st of March 2021 till 31 August 2021. There is a significant change regarding fetal movements in Betamethasone group only. There is a significant increase regarding umbilical artery RI in both groups, the increase was higher in Dexamethasone but still in normal range. Conclusion is dexamethasone causes significant decrease in middle cerebral artery decrease after one week but still in normal range. There was a significant increase regarding umbilical artery RI but in Dexamethasone was higher however still in normal range. In our study There was a significant decrease regarding fetal movements in Betamethasone group only post treatment one day and one week.

DOI

10.21608/aujv.2023.331249

Keywords

Betamethasone, Steroids, Intrauterine growth restriction, Fetal Doppler, fetal movements

Volume

5

Article Issue

3

Related Issue

44856

Issue Date

2023-09-01

Receive Date

2023-12-19

Publish Date

2023-09-01

Page Start

31

Page End

38

Print ISSN

3009-7819

Online ISSN

3009-6685

Link

https://aujv.journals.ekb.eg/article_331249.html

Detail API

https://aujv.journals.ekb.eg/service?article_code=331249

Order

331,249

Type

Original Article

Type Code

1,261

Publication Type

Journal

Publication Title

Al-Azhar University Journal of Medical and Virus Researches and Studies

Publication Link

https://aujv.journals.ekb.eg/

MainTitle

Comparative Study between Effect of Dexamethasone and Betamethasone used for Fetal Lung Maturity on Daily Fetal Movement Count and Doppler Flow Velocity Waveforms

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Type

Article

Created At

25 Dec 2024