Sugar beet (Beta vulgarisL.) is an important cash crop for the production of sugar beet grown in temperate regions. Often, fungal leaf diseases infect the sugar beet crop during the season, causing significant yield reductions.  The efficacy of some chemical fungicides to control the infection by the disease  and their impact on yield and sugar content was studied. The obtained data showed that plants and yield traits were significantly exceeded by applying fungicides used. Plants treated with Eminent recorded the highest efficiency regarding disease management as well as root weight, TSS, sugar percentage and purity followed by Nativo then Microthiol. In addition, plants sprayed with Eminent recorded the highest content of total phenols and peroxidase activity followed by Nativo and Microthiol. Only Nativo was safe for human after harvest that detected maximum residue level (MRL) ratio 0.02 at harvest. On the other hand, Eminent was the most dangerous to human, where recorded the highest residues at harvest and after 14 days of harvest. Foliure fungicide didn't show any decline in their residue at 14 days after harvest.