Background: Residual Ovarian Syndrome is a well-known gynecological complication that can negatively impact woman's life. The aim of this study was to examine the effect of nursing educational programs on sexual function and stress levels among women with residual ovarian syndrome. Method: A quasi-experimental design (one group pre/post test) was adopted to test the proposed hypotheses. A purposive sample of 30 women was recruited. This study was conducted at Obstetrics and Gynecology Outpatient Clinic at Menoufia University Hospital, Shebinelkom, Menoufia Governorate, Egypt. Three tools were used: I.Structured interview schedule; II. 6-items female sexual function index (FSFI-6); and III. Perceived stress scale (PSS).Results: There was a highly statistically significant difference in the mean sexual function index score between pre-intervention and post-intervention within women (p<0.001).Concerning stress level, 53.3% of women disclosed high stress at pre-intervention this was significantly decreased to 13.3% at post-intervention (p<0.001).The study finding revealed that, there was a highly statistically significant correlation between Sexual function and perceived stress at post-intervention (p<0.001).Conclusion: Women who participated in the nursing educational program experience an improvement in sexual function and a lower stress level. Recommendation: Women with residual ovarian syndrome should be provided with adequate health knowledge and practice in order to reduce their suffering through conducting nursing educational program.