Background: Providing video-assisted teaching programs to pregnant women at risk for preeclampsia is very important and will lower maternal, fetal, and neonatal morbidity and mortality. The aim of this study was to examine the effect of video-assisted teaching programs on the Knowledge, practices, and attitude of pregnant women at Risk for Preeclampsia. Method: Quasi-experimental research design (pretest/posttest) was adopted. A purposive sample of 120 pregnant women at Risk for Preeclampsia was recruited based on specific criteria. This study was conducted at EL Shohada Hospital at the Department of Obstetrics and Gynecology in the Menoufia government. Four tools were used: 1. A structured Interviewing questionnaire; II. Pregnant women's knowledge regarding preeclampsia; III. Pregnant women's practice regarding pre-eclampsia preventive behavior; IV. Pregnant women's attitude questionnaire regarding preeclampsia prevention. Results: In the pre-video-assisted teaching program 51.7%, 89.2%, and 47.5% of pregnant women had poor knowledge, unsatisfactory practices, and a negative attitude respectively. While post-intervention, (60%, 88.3% and 70% of pregnant women had high knowledge, satisfactory practice, and a positive attitude respectively. Pre- and post-intervention differences in women's overall preeclampsia knowledge, practices, and attitudes were highly statistically significant (p < 0.001). Conclusion: Pregnant women who participated in Video-assisted teaching programs experience an expedited acquisition of knowledge, promote caring practices, and encourage a positive attitude toward the prevention of preeclampsia during pregnancy. Recommendation: Applying video-assisted teaching programs during antenatal care for pregnant women at risk of preeclampsia will improve their knowledge, practices, and attitude regarding preeclampsia disease.