Background: Atrial fibrillation is the most frequent and well-managed arrhythmia in the world. Regular physical activity and exercise training are essential for secondary prevention of cardiovascular illnesses. Despite recent developments in holistic treatment pathways for patients with atrial fibrillation, pedometers have lately received attention as an effective tool in the promotion of physical activity. Therefore, the aim of the study was to evaluate the effect of pedometer telenursing instructions on steps count and pulse rate in atrial fibrillation patients. Subject and Methods: A quasi-experimental research design was carried out in the cardiovascular outpatient at Ain Shams and Suez-Canal University Hospitals. Subject: In this study, a convenient sample of 110 adult patients split into two equal groups "study and control" was enrolled. Tools: This study employed two tools: tool (I), a structured interview questionnaire to assess personal and clinical data of patients, & tool (II) a steps count and pulse rate monitoring record. Results: Mean±SD of steps count and pulse rate in the study group were (3585.3 ±1689.6, 4282.5±2005.3, 6400.3±2759.6) and (76.6 ±14.8, 71.0 ±8.6, 70.6 ±5.4) at the pre/post and follow-up instructions respectively with statistically significant difference between the study and the control groups at the post and follow-up phases. Conclusion: There was a statistically significant positive effect of pedometer telenursing instructions on steps count and pulse rate stability in atrial fibrillation patients. Recommendation: Design audiovisual materials about aerobic exercises that the patient with atrial fibrillation should practice to be presented during patient waiting times.