Objective: To determine the effect of chronic renal failure disease and hemodialysis on auditory system compared to normal control persons. Method: The current study comprised 50 patients (28 men and 22 women) with chronic renal failure receiving haemodialysis, with ages ranging from 6 to 65 years, and 50 controls (six men and thirty-four women), with ages ranging from 34.8 to 11.71 years (15-60years). Each individual underwent testing using brainstem auditory evoked potential, tympanometry, and pure tone audiometry (ABR). Tympanometric values, auditory evoked potentials, and the means of air and bone conduction at each frequency were computed for the study groups. Results: Pure tone audiometry was significantly higher among patients with chronic renal failure at all pure tone audiometry frequencies as compared with healthy controls with a statistically significant p-values(p value 0.0004, 0.0004, 0.0006, 0.0006, 0.0005, and 0.0009) and more obvious at high frequencies. Conclusion: According to this study, hearing loss was more common in haemodialysis patients with chronic renal failure. Most patients exhibited a mild sensorineural hearing loss that was mostly noticeable at higher frequencies. This study also showed that, in contrast to healthy controls, those with end-stage chronic renal failure receiving haemodialysis have delayed neuronal conduction throughout the auditory circuit