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Detection of cerebral microbleeds by Susceptibility-Weighted-MR-Imaging in elderly population in comparison with cognitive tests

Article

Last updated: 25 Dec 2024

Subjects

-

Tags

Diagnostic

Abstract

Background: Neuroimaging results related to cerebral microbleeds are becoming more well known. Significant advancements have been made in recent years, notably in the creation of improved MRI detection technologies and their application to various diagnostic investigations of neuropsychological illnesses. The purpose of this research was to determine if susceptibility weighted imaging can identify cerebral microbleeds in older people and determine whether these microbleeds were associated with cognitive dysfunction. Results: This study was an observational cross-sectional study performed on 58 elderly subjects above the age of 50. Cognitive functions for the included subjects were assessed using Paced Auditory Serial Addition Test (PASAT), Benton Visual Retention test (BVRT) and Paired Associate Learning test (PALT). All included subjects underwent routine MRI and susceptibility weighted images. The mean values for PALT, BVRT, PASAT scores were 10.2±3.2, 12.7±3.4, and 27.9±10.9 respectively. There were statistically significant negative correlations between the scores of PALT, BVRT, PASAT, and lobar (P-value <0.001 in all tests) and total number of microbleeds (P-value= 0.005, 0.016, 0.001 respectively). In addition, there was a statistically significant negative correlation between PASAT score and number of infra-tentorial microbleeds (P-value= 0.022). Conclusions: The occurrence of cerebral microbleeds detected by Susceptibility-Weighted-MR-Imaging had a significant impact on cognitive function. The Susceptibility-Weighted-MR-Imaging can be used as a screening for early detection of microbleeds in patients with impaired cognitive functions and so, we can avoid the consequences of CMBs specially in male subjects with associated comorbidities as diabetes and hypertension.

DOI

10.21608/ejmr.2023.189895.1330

Keywords

Cerebral Microbleeds, Cognitive Functions, Susceptibility Weighted Imaging, MRI

Authors

First Name

Sahar

Last Name

Abd elsalam

MiddleName

Mahmoud

Affiliation

Faculty of Medicine, Beni-Suef University, Egypt , Radiology department.

Email

sahr.abdelsalam@med.bsu.edu.eg

City

Beni-Suef

Orcid

0000-0003-3621-4353

First Name

Ahmed

Last Name

Said

MiddleName

Hesham Mohamed

Affiliation

Faculty of Medicine, Beni-Suef University, Egypt , Radiology department.

Email

heshamsaeed@med.bsu.edu.eg

City

-

Orcid

-

First Name

Ahmed

Last Name

Haraz

MiddleName

Ibrahim

Affiliation

Faculty of medicine , 6 October University, Radiology department.

Email

dr_ahmed_harraz2014@yahoo.com

City

-

Orcid

-

First Name

Mona

Last Name

Tawfek

MiddleName

Hussien

Affiliation

Faculty of medicine, Beni-Suef University, Egypt , Neurology department.

Email

mona.neuro@yahoo.com

City

Beni-suef

Orcid

-

First Name

Ahmed

Last Name

Zidan

MiddleName

Abdel Fattah

Affiliation

Faculty of Medicine, Beni-Suef University, Egypt , Radiology department.

Email

ahasq@yahoo.com

City

beni suef

Orcid

-

Volume

5

Article Issue

1

Related Issue

45399

Issue Date

2024-01-01

Receive Date

2023-01-26

Publish Date

2024-01-01

Page Start

61

Page End

79

Print ISSN

2682-4396

Online ISSN

2682-440X

Link

https://ejmr.journals.ekb.eg/article_338985.html

Detail API

https://ejmr.journals.ekb.eg/service?article_code=338985

Order

338,985

Type

Original Article

Type Code

1,224

Publication Type

Journal

Publication Title

Egyptian Journal of Medical Research

Publication Link

https://ejmr.journals.ekb.eg/

MainTitle

Detection of cerebral microbleeds by Susceptibility-Weighted-MR-Imaging in elderly population in comparison with cognitive tests

Details

Type

Article

Created At

25 Dec 2024