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Efficacy of intrathecal Dexamethasone to decrease the incidence of postspinal hypotension in geriatric patients undergoing orthopedic surgery.

Article

Last updated: 25 Dec 2024

Subjects

-

Tags

Surgery ·

Abstract

Background: It might be difficult to treat hypotension after spinal or epidural anesthesia in older adults. There is a danger of volume overload or cardiac compromise when PSA hypotension is treated with fluids (colloids or crystalloids) or vasoconstrictors. When decreased peripheral vascular resistance is present, dexamethasone is utilized as a treatment. Methods: Eighty patients, aged 60 years or more were recruited to receive a single preoperative intrathecal dose of dexamethasone 8 mg (dexamethasone group) (40 patients), and 40 patients were given placebo receiving normal saline (Control group) in a randomized, double-blind trial. Variations in blood pressure and heart rate in addition to the needs of ephedrine and/or atropine following spinal anesthesia (SA) were recorded.  Result: The mean age of patients in 4dexamethasone group was 67.8±6.8 years and most of them were females (72.5%). The mean arterial blood pressure showed no significant difference between the studied groups regarding their baseline and all measures of mean arterial blood pressure. However, at all measures the MAP was higher in the dexamethasone group than the control group. Conclusion: Post-spinal anesthesia hypotension in elderly patients was less common after receiving a single preoperative intrathecal dose of dexamethasone 8 mg than control.

DOI

10.21608/ejmr.2023.228368.1440

Keywords

Spinal anesthesia, geriatrics, dexamethasone, hypotension

Authors

First Name

Ahmed

Last Name

AL Sharaway

MiddleName

Mustafa

Affiliation

Assistant Professor of Anesthesia Surgical Intensive Care and Pain Management, Faculty of Medicine, Beni-Suef University

Email

drshaarawy@gmail.com

City

-

Orcid

-

First Name

Hanaa

Last Name

Mohamed

MiddleName

Fathy

Affiliation

M.B.B.Ch, Faculty of Medicine, Beni-Suef University, Resident of Anesthesia Surgical Intensive Care and Pain Management, Faculty of Medicine, Beni-Suef University

Email

hanaelnager2011@gmail.com

City

Beniseuf

Orcid

-

First Name

Mohamed

Last Name

Abd elkader

MiddleName

-

Affiliation

Lecturer of Anesthesia Surgical Intensive Care and Pain Management, Faculty of Medicine, Beni-Suef University

Email

mosobing@gmail.com

City

-

Orcid

-

Volume

5

Article Issue

1

Related Issue

45399

Issue Date

2024-01-01

Receive Date

2023-08-09

Publish Date

2024-01-01

Page Start

34

Page End

40

Print ISSN

2682-4396

Online ISSN

2682-440X

Link

https://ejmr.journals.ekb.eg/article_335800.html

Detail API

https://ejmr.journals.ekb.eg/service?article_code=335800

Order

335,800

Type

Original Article

Type Code

1,224

Publication Type

Journal

Publication Title

Egyptian Journal of Medical Research

Publication Link

https://ejmr.journals.ekb.eg/

MainTitle

Efficacy of intrathecal Dexamethasone to decrease the incidence of postspinal hypotension in geriatric patients undergoing orthopedic surgery.

Details

Type

Article

Created At

25 Dec 2024