Cleft palate is among the commonest craniofacial abnormality with an incidence of about 1 in every 2000 to 2500 births. Cleft palate repair is a challenging procedure with multiple operations described for the same anomaly. The aim of this study is to improve the outcome of cleft palate repair by using fibrin glue as an adjuvant in the  repair with its effect on lowering postoperative complications. A prospective study was carried on 30 patients for primary cleft palate repair operated upon by double flap palatoplasty with the use of human fibrin glue in the repair. Fibrin glue was injected between the oral and nasal layers of palate and at suture line. Six cases showed postoperative complications, with rate of complication 23.3 %, Three of them (10%) were complicated by oronasal palatal fistula. Two of them (6.6%) were small and closed spontaneously within 2 months postoperatively and the third case (3.3%) was presented primarily by local wound infection and later on had showed an oronasal fistula and needed surgical repair, two cases(6.6%) were complicated by upper airway obstruction immediately postoperative and one case (3.3%) was complicated by reactionary hemorrhage. It was concluded that fibrin glue is an adjuvant that can be used with surgical repair of cleft palate for improving surgical outcome and lowering postoperative complications.