The importance of the applications and uses of Nanomaterials in the field of textiles is increasing, and it has become a major and influential role with the progress of scientific research, and with the requirements of life, nanotechnology has raised the efficiency of traditional materials, making clothing fabrics more resistant to external factors and making them maintain the cleanliness of the environment to achieve sustainable development, as they resist Bacteria and fungi, in addition to the self-cleaning process for the clothes of workers in the field of inks, to adapt to the surrounding environment. Inks pose a greater risk to the skin of workers, so care must be taken The safety of workers through the use of ink-protective clothing fabrics, which must have special specifications to protect workers' skin and be characterized by ease of cleaning and preservation of the aesthetic appearance and consumable life of the fabrics, through the use of nanotechnology, which prepares the fabrics with titanium dioxide, with the use of natural materials such as cotton (Cotton Open end and Cotton Compact). The research aims Achieving Sustainable development by using Treatment with Titanium Dioxide to produce protective Clothing fabrics for Workers in the field of Self-Cleaning Inks , they are self-cleaning, by achieving the best mixing ratio, the best spinning method, and the best implementation method. Sixteen samples were produced with a quilted implementation method and a decorative composition, with four mixing ratios with cotton material, ring end spinning, and various tests were conducted, namely measuring the thickness test and the air permeability test. The square meter weight, tensile strength, elongation and self-cleaning tests were tested, and most of the samples achieved the required results. Statement of the Problem   The problem of the research lies in the lack of use of new materials manufactured using nanotechnology in the fabrics used by workers in the field of inks. Increasing the problems faced by workers in the field of inks due to stains and dust There is an urgent need to remove stains using detergents and continuous washing, which affects the useful life of fabrics Therefore, solutions must be provided to these problems to produce fabrics for workers in the field of inks to achieve sustainable development using self-cleaning titanium dioxide treatment. Research Significance: Finding solutions to achieve sustainable development by using treatment with titanium dioxide to produce protective clothing fabrics for workers in the field of self-cleaning inks. Research Objective -        Identifying the nature of nanotechnology, and studying the equipment with this property as a material that achieves intelligence in achieving sustainable development. -        Increasing awareness of the importance of this technology and its application among those working in the field of inks. Research Hypothesis    -        Chemical treatment using Nanotechnology affects the properties of fabrics of clothing used by workers in the field of inks -        The difference in the mixing ratio of wefts affects the extent of protection of the clothing of workers in the field of inks -        The type of spinning affects the self-cleaning property   -        The execution method affects the self-cleaning property Research Methodology The research is based on the analytical method and the experimental method. Search Results The study proved that: -    The thickness decreases as the mixing ratio with ring-spun cotton decreases. This is due to the difference in the open-end spinning method and the bonding of the fibers to the twines from the inside out, unlike ring-spinning. After treatment with titanium dioxide, the thickness decreases. -        The weight per square meter increases as the mixing ratio with ring-spin cotton decreases. Cotton Compact has a slightly higher weight per square meter than open-end yarn. Treating with titanium dioxide improves the properties of the fabrics, so the weight per square meter decreases. -        Air permeability decreases as the mixing ratio with ring-spin cotton decreases and is treated with titanium dioxide. The properties of the fabrics improve and air permeability increases. -        The Tensile strength increases in the direction of the wefts as the mixing ratio with ring-spin cotton decreases, and the treatment with titanium dioxide improves the properties of the fabrics. The tensile strength increases in the direction of the wefts. -        The Elongation in the direction of the wefts increases as the mixing ratio with ring-spin cotton decreases, and the treatment with titanium dioxide improves the properties of the fabrics. The elongation in the direction of the wefts decreases. -        The Degree of Self-Cleaning increases as the mixing ratio with ring-spin cotton decreases, and the degree of self-cleaning occurs after treatment. The Three Best samples characterized by the Self-Cleaning feature and all the functional properties, for the production of clothing fabrics for workers in the field of inks, sample No. 1 (3 Cotton ring spin: 1 Cotton open-end (decorative)), and sample No. 2 (3 Cotton ring spin: 1Cotton Compact (decorative)) Sample No. 3 ( 1 Cotton ring spin: 1 Cotton Compact (lined