The effects of applying organic fertilizers rather than chemical ones on quinoa plants (Chenopodium quinoa Willd.) were investigated throughout two winter seasons in 2020–2022 and 2022–2023, at the Environmental Agricultural Sciences Faculty Experimental Farm at Arish University in the El-Arish area, North Sinai. "Danish KVL3704" cv. of quinoa was sowed on October 26th for both seasons. Five distinct treatments of chemically recommended fertilizers (RCF) and organically recommended fertilizers (ROF) were utilized in the study, along with the replacement of RCF with part of organic fertilizer. The treatment of using 25% RCF + ROF + 75% RCF as organic fertilizer recorded the highest value for plant height, number of leaves and branches, fresh and dry weight of leaves and shoot, weight of 1000 grains, and leaves content of phosphorus and potassium, while the treatment of 50% RCF + ROF + 50% RCF as an organic fertilizer recorded the highest grain yield (ton fed-1), and the highest leaves content of nitrogen and protein after 90 days of sowing, and the trend was different with the leaves content after 60 days of sowing, where, the treatment of 0.0% RCF + ROF at 100% recorded the highest value. As for the grains content of nitrogen and protein, the highest values were with the treatment of 75% RCF + (ROF) + 25% RCF as an organic fertilizer, and the treatment of 0.0% RCF + ROF 100% of RCF as organic fertilizers for phosphorus and potassium content in grains.