At the Experimental Farm of Environmental Agricultural Sciences Faculty, Arish University, North Sinai, Egypt, a field study was carried out during two summer seasons of 2021 and 2022. The aim of this study was studying how tomato plants (Solanum Lycopersicon L.) respond if organic fertilizer utilized in El-Arish area instead of chemical fertilizer. In both seasons, "GS12 F1" tomato seedlings were transplanted on April 9. The experimental unit had a drip irrigation system and was 12 m² in area (10 m in length and 1.2 width), organic fertilizer was cow manure. The study employed five alternative treatments of recommended chemical (RCF) and recommended organic fertilizers (ROF) with replacing the RCF with equivalent part of organic fertilizer. The highest values of vegetative growth traits, fresh weight, dry weight, marketable yield, and the lowest unmarketable yield of tomato were not significantly different among the treatments of 0.0% of RCF + ROF + 100% of RCF (equivalent for 100% of chemical fertilizer as organic fertilizer) applied in both seasons, 25% of RCF + ROF with 75% of RCF (equivalent for 75% of chemical fertilizer as organic fertilizer), 50% of RCF + ROF+50% of recommended RCF (equivalent for 50% of chemical fertilizer as organic fertilizer), and 75% of RCF+ROF+25% RCF (equivalent for 25% of chemical fertilizer as organic fertilizer).