The shipbuilding and heavy manufacturing industries are looking for a novel welding technique to weld high-strength steel alloys with thicknesses above 25 mm. Submerged arc welding (SAW) has been the “go-to" joining process for thick material from both sides. However, using SAW alone requires thick plates to be flipped over multiple times during welding to minimize the effects of distortion and uses a large volume of weld metal. This paper presents research on the feasibility of welding thick, high-strength steel plates in a combined, sequential processing approach utilizing HLAW and SAW. The development activity entails HLAW processing the weld joint's first pass to achieve an approximate 18 mm root penetration, followed by SAW to complete the joint (38 mm). Mechanical properties, impact toughness, and microhardness hardness distribution in specific zones of one side butt multiple pass welded joints are analyzed in correlation with a microstructure in specific zones of the welded joint. The paper also discusses the applicable standards and recommendations for welding those steels, from the aspect of applications in the design of steel welded constructions. Based on the carried-out analysis and results obtained in experiments, the applied welding technology minimizes the volume of weld metal needed to complete the joint. It achieves requisite performance mechanical properties while reducing material preparation costs and labor. This joining process approach is expected to increase capabilities for shipbuilding, heavy manufacturing, and oil and gas industries.