ABSTRACT Individuals with peripheral arterial disease (PAD) could experience increased pain, intermittent claudication (IC), disability, decreased gait distance, activity limitations in activities of daily living. The current study was aimed to investigate the efficacy of progressive resistive exercises on ankle brachial index in patients with chronic lower limb ischemia. Thirty male patients with symptomatic PAD aged from 50 to 60 years old were selected. They were randomly assigned into two groups equal in number; Patients in Group (A) received resistive exercise training program in the form of series of exercises using free weights in addition to their regular medical treatment, while Group (B) patients received their regular medical treatment only. Sessions were carried out three times per week, for a total of twelve week period.  Ankle brachial pressure index (ABI) and body mass index (BMI) were recorded in the two groups at two intervals: the starting of the study (pre-training) and at the end of the 12 week (post training). It was observed that  there was non-significant change in ABI of study and control groups (p > 0.05). While there was a significant decrease in BMI of the study group post treatment compared with that pre-treatment (p > 0.001); and there was non-significant change in BMI of control group (p > 0.05). It could be concluded that application of progressive resistive exercise couldn't affect ankle brachial index  in patients with peripheral arterial disease.