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Rhinoorbital mucormycosis - Unveiling the hidden menace : A Case Series

Article

Last updated: 25 Dec 2024

Subjects

-

Tags

Medical mycology

Abstract

Background: Mucormycosis is a life-threatening angioinvasive infection caused by filamentous fungi of the order Mucorales. The disease occurs commonly in immunocompromised individuals with hematological malignancies or those undergoing stem cell transplantation. Major risk factors include immunosuppression, uncontrolled diabetes, iron overload, and trauma. Diagnosis and treatment remain challenging due to inherent antifungal resistance. Depending on the host's immunological condition and route of infection, clinical and radiological symptoms differ across patients. Case Series:  We present two cases of rhino-orbital mucormycosis in middle-aged individuals who were reported to the outpatient department of North Bengal Medical College and Hospital with varied clinical presentations. Neither patients had any history of novel coronavirus disease 2019 (COVID-19) infection. Our report demonstrates the role of radiological investigation; Magnetic Resonance Imaging (MRI) for prompt confirmation of clinical suspicion with adequate confidence. Conclusion: Invasive mucormycosis has been found to cause high morbidity and mortality with death rates up to 50%. Therefore, it is critical to maintain a high degree of suspicion for infection since early diagnosis and initiation of necessary treatment improves patient outcomes. MRI helps in early diagnosis of the condition and helps in quick treatment initiation thus improving patient outcome.

DOI

10.21608/mid.2023.243757.1640

Keywords

mucormycosis, Rhino-orbital mucormycosis, Magnetic Resonance Imaging, Angioinvasion

Authors

First Name

Shibam

Last Name

Kundagrami

MiddleName

-

Affiliation

North Bengal Medical College and Hospital, Darjeeling, India

Email

shibamkundagrami@gmail.com

City

-

Orcid

0009-0001-4920-9265

First Name

Siddhartha

Last Name

Basak

MiddleName

-

Affiliation

North Bengal Medical College and Hospital, Darjeeling, India

Email

siddharthabasak42@gmail.com

City

-

Orcid

0009-0009-1198-9444

First Name

Uddalok

Last Name

Das

MiddleName

-

Affiliation

Department of Radiodiagnosis, North Bengal Medical College and Hospital, Darjeeling, India

Email

rikdas05@gmail.com

City

-

Orcid

0000-0001-6970-7520

Volume

5

Article Issue

3

Related Issue

49567

Issue Date

2024-08-01

Receive Date

2023-10-20

Publish Date

2024-08-01

Page Start

934

Page End

938

Print ISSN

2682-4132

Online ISSN

2682-4140

Link

https://mid.journals.ekb.eg/article_326539.html

Detail API

https://mid.journals.ekb.eg/service?article_code=326539

Order

7

Type

Short Reports (case reports)

Type Code

1,159

Publication Type

Journal

Publication Title

Microbes and Infectious Diseases

Publication Link

https://mid.journals.ekb.eg/

MainTitle

Rhinoorbital mucormycosis - Unveiling the hidden menace : A Case Series

Details

Type

Article

Created At

25 Dec 2024