Beta
ManageSearchChatDiscover
263052

Detection of aztreonam, meropenem and imipenem resistant Gram negative bacteria from inpatient department in Federal Medical Center (FMC), Birnin, Kebbi, Nigeria

Article

Last updated: 25 Dec 2024

OverviewSimilar Items

Subjects

-

Tags

Antimicrobial resistance

Abstract

Background: Antibiotic resistant infections were responsible for the deaths of 1.27 million people, with an overall 4.95 million deaths associated with complications from resistant bacterial infections globally. Aim: This study determined the antibiotics; aztreonam (ATM), meropenem (MEM) and imipenem (IMP) resistant Gram negative bacteria from inpatient department in FMC, Birnin Kebbi. Methods: Thirty (30) samples from different fomites in the inpatient department were aseptically collected using swab sticks. Streak plate technique was used to characterize and identify the bacterial isolates, then disc diffusion technique was employed to check the resistance pattern of the isolates to the antibiotics as in EUCAST guidelines version 12.0. Results: The biochemical technique further confirmed the occurrence of; Escherichia coli (E. coli) (35%), Pseudomonas aeruginosa (30%), Klebseilla pneumonia (20%) and Acinetobacter baumannii (A. baumannii) (15%). On the antibiotic resistance screening, E. coli and A. baumannii were found multi-drug resistant (MDR) to the antibiotics. The remaining isolates show resistance to the antibiotics except Pseudomonas aeruginosa and Klebsiella pneumonia were found sensitive to MEM and IPM respectively. Conclusion: Bacteria isolated are highly drug resistant to the antibiotics. The need for routine environmental sanitation, proper personal hygiene among the hospital participants, drug repositioning and molecular assay for rapid detection of MDR bacteria.

DOI

10.21608/mid.2022.160057.1378

Keywords

Azetreonam, Meropenem, Imipenem, Inpatient Department, MDR

Authors

First Name

Bilyaminu

Last Name

Jega

MiddleName

-

Affiliation

Department of Microbiology, Faculty of Life Sciences, Kebbi State University of Science an Technology, Aliero, Kebbi State, Nigeria

Email

abunasmatu@gmail.com

City

Birnin Kebbi

Orcid

0000-0001-9134-5909

First Name

Mustapha

Last Name

Aliyu

MiddleName

-

Affiliation

Department of Microbiology, Faculty of Life Sciences, Kebbi State University of Science an Technology, Aliero, Kebbi State, Nigeria

Email

mustaphasahabi1984@gmail.com

City

Birnin Kebbi

Orcid

0000-0003-1294-2196

First Name

Muhammad

Last Name

Muhammad

MiddleName

-

Affiliation

Department of Microbiology, Faculty of Life Sciences, Kebbi State University of Science an Technology, Aliero, Kebbi State, Nigeria

Email

deenshams2000@gmail.com

City

Birnin Kebbi

Orcid

0000-0003-3328-6685

First Name

Musa

Last Name

Isah

MiddleName

-

Affiliation

Department of Microbiology, Faculty of Life Sciences, Kebbi State University of Science an Technology, Aliero, Kebbi State, Nigeria

Email

isahmg97@gmail.com

City

Birnin Kebbi

Orcid

0000-0002-4468-9335

First Name

Abubakar

Last Name

Sani

MiddleName

-

Affiliation

Department of Microbiology, Faculty of Life Sciences, Kebbi State University of Science an Technology, Aliero, Kebbi State, Nigeria

Email

abubakarsani464@gmail.com

City

Birnin Kebbi

Orcid

0000-0001-6986-2408

First Name

Aisha

Last Name

Inuwa

MiddleName

-

Affiliation

Department of Microbiology, Faculty of Life Sciences, Kebbi State University of Science an Technology, Aliero, Kebbi State, Nigeria

Email

aishami222@gmail.com

City

Birnin Kebbi

Orcid

-

Volume

5

Article Issue

1

Related Issue

45807

Issue Date

2024-02-01

Receive Date

2022-09-01

Publish Date

2024-02-01

Page Start

295

Page End

300

Print ISSN

2682-4132

Online ISSN

2682-4140

Article File

MID_Volume 5_Issue 1_Pages 295-300.pdf

PDF . 674.5kB

Link

https://mid.journals.ekb.eg/article_263052.html

Detail API

https://mid.journals.ekb.eg/service?article_code=263052

Order

31

Type

Original Article

Type Code

1,157

Publication Type

Journal

Publication Title

Microbes and Infectious Diseases

Publication Link

https://mid.journals.ekb.eg/

MainTitle

Detection of aztreonam, meropenem and imipenem resistant Gram negative bacteria from inpatient department in Federal Medical Center (FMC), Birnin, Kebbi, Nigeria

Details

Type

Article

Created At

25 Dec 2024